This study assesses the implementation of the Individualized Positive Psychosocial Interaction (IPPI) as part of a 15-site Ohio nursing home quality improvement program. Participating homes reported strong organizational commitment and efficacy, with 65% completing the program successfully. These communities conducted 638 IPPIs with 65 residents. Nearly half (47%) of the IPPI experiences resulted in positive mood changes for residents. Overall, nursing homes found the IPPI highly acceptable, feasible, and appropriate, indicating its effectiveness in addressing distress communication among residents with moderate to severe dementia. The findings underscore the potential of brief, person-centered interventions in enhancing the well-being of individuals living with dementia in long-term care settings.